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Source: Link Testing Instruments Co.,Ltd.

I. Glass Container Internal Pressure Resistance Testing: A Critical Barrier to Pharmaceutical Packaging Material Safety

The quality of pharmaceutical packaging materials is directly related to medication safety, with the physical strength of glass containers being a key indicator. Internal pressure testing, conducted in accordance with the national pharmaceutical packaging material standard YBB00172003-2015, "Glass Container Internal Pressure Resistance Test Method," is a key method for evaluating the ability of glass bottles, ampoules, and other materials to withstand internal pressure. It is crucial for preventing pressure-induced breakage and leakage during transportation, storage, or use, and serves as a fundamental line of defense for ensuring drug stability and patient safety.

 

II. Analysis of the Core Requirements of the YBB00172003-2015 Standard

This standard provides an authoritative and unified test method for the internal pressure resistance of glass containers. Key requirements include:

1. Test Principle: Using the hydraulic method, increasing liquid pressure is continuously applied to a sealed glass container until the container ruptures or reaches a predetermined pressure value.

2. Key Parameter - Pressurization Rate: The standard strictly specifies the rate of pressure increase, typically between 0.4 MPa/s and 0.6 MPa/s (or as required by specific product standards). A stable and controllable pressure increase rate is essential for accurate and comparable results.

3. Acceptance Determination: The specimen must withstand the minimum internal pressure specified in the standard without rupture. Specific values should refer to the pharmaceutical packaging material standards for the corresponding product (e.g., the YBB series standards specify requirements for different ampoules and infusion bottles).

4. Specimen Preparation and Conditioning: Specimens must be clean and undamaged, and conditioned under specified temperature and humidity conditions to ensure a consistent testing environment.

5. Result Presentation: Accurately record the burst pressure (MPa) for each specimen and calculate the average.

 

III. Link Testing LTGPT-02 Glass Bottle Internal Pressure Tester Specifications

LTGPT-02 Bottle Internal Pressure Tester

The GPT-02 Glass Bottle Internal Pressure Tester, independently developed and manufactured by Link Testing Instruments Co., Ltd., is a professional device that meets the YBB standard. Key technical specifications are as follows:

Technical parameter	LTGPT-02	Explanation
Pressure range	0.5 ～ 7MPa	Meets common glass container testing needs
Resolution	0.001 MPa	High-precision pressure display
Test station	Single station	Standard configuration
Control method	Computer control + touch screen	Easy and intuitive operation
Data Management	Automatic storage and report printing	Meet GMP requirements
Safety protection	Overpressure protection and protection cover	Ensure operator safety

 

The equipment is precisely designed and features stable and accurate pressure rise rate control, effectively ensuring that the testing process strictly complies with YBB standards and that the test results are reliable. It is suitable for pharmaceutical companies, pharmaceutical packaging material manufacturers, and quality inspection agencies to conduct quality control and delivery inspections on the internal pressure resistance of glass containers of different specifications.

 

IV. Conclusion

Strictly adhering to the YBB00172003-2015 standard for glass container internal pressure resistance testing is an essential component of the pharmaceutical packaging material quality control system. Selecting reliable testing equipment that meets standard requirements provides a solid guarantee for the sealing integrity and transportation safety of pharmaceutical packaging.

For more details please visit www.linktesting.org